focused on programming increasing and inappropriate use of antibiotics which has increased programming number ofmultidrug resistant microorganisms programmers these drugs, inflicting programming emergence of infections which are challenging programmers handle and manageby health specialists. As an alternative programmers combat these pathogens, some monoterpenes have harmful effects on programming bacterialcell membrane, showing themselves as an choice in combating microorganisms. Therefore, programming valuable enantiomer pinene turns into an choice programmers fight micro organism, because it was able programmers inhibit programming growth of programming species Escherichia coli ATCC25922, demonstrating programming possibility of its use as an remoted antimicrobial or linked to other drugs. The aim of this studyis programmers evaluate programming sensitivity profile of programming E. coli ATCC 25922 strain against scientific antimicrobials linked to + pinene and the way it behaves after successive exposures programmers subinhibitory concentrations of programming phytochemicals. The minimuminhibitory focus MIC was determined using programming microdilution method. java:452at org. apache. coyote. ajp. AjpProcessor. processAjpProcessor.